Keys and Locks

General Locks

Unlocked

This is always accessible.

Human Form Locks

Must be in Human Form to use these.

Normal Weapon Locks

These require having acquired the appropriate upgrade, and you must have ammo available.

Normal Door

These can be opened with any weapon. They also open automatically if the player is launching.

Normal Gate

These can be opened with any weapon from the correct side (1-way). These can also be opened from the wrong side with the Quantum weapon.

Missile Door

Requires a Missile to leave the room.

Missile Gate

Requires a Missile to raise the gate from the correct side. (1-way).

Missile Block

Requires a Missile to break.

Big Missile Door

Requires a Big Missile to leave the room.

Big Missile Gate

Requires a Big Missile to raise the gate from the correct side. (1-way).

Big Missile Block

Requires a Big Missile to break.

Elemental Weapon Locks

These require that the weapon has been collected and that it has been activated with its Elemental Orb which can be acquired by killing the elemental boss. You must also have ammo available.

Elemental Door

Requires the matching Elemental Weapon to leave the room.

Elemental Gate

Requires the matching Elemental Weapon to raise the gate (1-way).

Elemental Block

Requires the matching Elemental Weapon to break.

Elemental Boss Locks

Biome Boss Door

Requires the matching biome boss has been killed. Can be opened with anything as long as you have the matching Orb. They go from being indestructible to being normal doors.

Suit Locks

These require that you both have the suit and that it is enabled.

???

Defense Suit makes this possible.

Water

Movement in water is dramatically slowed down and more difficult. Liquid Suit makes it like normal movement.

Mud

Movement in mud is near impossible. Liquid Suit makes it behave like Water.

Hot Area

Requires the Heat Suit to greatly reduce damage take over time in these areas. If the Defense Suit is also equipped, no damage is done at all.

Cold Area

Requires the Cold Suit to greatly reduce damage take over time in these areas. If the Defense Suit is also equipped, no damage is done at all.

Hot Water

Behaves like normal water with the Liquid Suit. It hurts you over time without the Heat Suit.

Cold Water

Behaves like normal water with the Liquid Suit. It hurts you over time without the Cold Suit.

Lava

Behaves like Mud with the Liquid Suit. Hurts you very quickly over time. Damage can be reduced with the Heat Suit and reduced more with the Defense Suit, but it will always hurt you.

Cat Form Locks

Cat Form is also required to be able to unlock any of the following locks.

Bomb Block

Requires a Bomb or Big Bomb to break.

Big Bomb Door

Requires a Big Bomb to leave the room.

Big Bomb Block

Requires a Big Bomb to break.